Your healthcare provider will give you a prescription for mifepristone/ misoprostol that may also include pain medication. You should call your pharmacy to ensure this medication is available.
- You will first take mifepristone orally. You may experience some spotting in the 24 hours that follow mifepristone. Some people find they do not experience any symptoms and continue to work during this time.
- 24-48 hours later, you will place 4 tablets of misoprostol in your vagina. The miscarriage will usually occur within 4-12 hours from the time you insert the misoprostol tablets.
- Your provider should arrange a telephone follow-up with you 1 week after you take the medication to ensure you have had the miscarriage.
You are likely to experience cramping and bleeding that lasts several hours. For many, heavy bleeding and severe cramping lasts 2-3 hours while the miscarriage is occuring. You may continue to feel symptoms of pregnancy such as nausea and fatigue until your miscarriage is completed.
After the passage of pregnancy tissue, you will continue to have some cramping and bleeding for up to 2 weeks. Bleeding after a miscarriage is often similar to a menstrual period.
It is not necessary for you to have an ultrasound after you have miscarried, unless you continue to have heavy bleeding following the miscarriage (soaking 1 pad per hour for more than 3 hours), or you experience ongoing bleeding or cramping 2 weeks after your miscarriage.
Side effects are usually mild and can include nausea, vomiting or diarrhea. Please alert your provider if you experience vomiting within 1 hour of taking mifepristone.
You may continue to breastfeed while taking this two drug combination.